Histology & Immunohistochemistry

WBR’s Histology offers a full set of histology services ranging from the collection of tissue samples to delivering the detailed study reports that contain all experimental procedures and their outcome.

You have the option to select any entry point and exit point in our workflow.

We will handle the following species, irrespective of tissues and strains.

  • Rats
  • Mice
  • Zebrafish Adult & Larvae
  • Hamsters
  • Beagles
  • Guinea Pigs
  • Rabbits
  • Other fish, invertebrates and plant tissue

We provide fast in-house processing by experienced and well-trained staff and work with highly reliable shipping companies to guarantee safe transfer of your valuable samples.

Dissection & Embedding

Just discuss your needs with us, and we take care of dissecting the target tissue, accurate trimming of the tissue block, fixation and embedding of your tissue samples. Highly standardized default procedures are established, but alternatives can be used upon request. We are experienced working RNase-free.

Fixation
  • Standard: 4% paraformaldehyde / 10% Neutral buffer Formalin
  • Alternatives: Glutaraldehyde, zinc, picric acid, ethanol etc Embedding
  • Standard: paraffin
Sectioning

Our expertise covers a wide range of sectioning techniques and tissue collection strategies. We process your samples according to the specific requirements of your project.

  • Rotary microtome (Leica)
  • Choose any orientation and specify the section thickness Collecting
  • Specify your collection scheme
Immunohistology & General Stainings

Staining Techniques and Applications:

We routinely perform both fluorescent and chromogenic immunostainings as well as general histological stainings and stainings for special applications. Additionally, we are happy to establish and optimize customized staining protocols for your specific needs.

Special Stainings:
  • Congo Red (amyloid plaques, tau tangles)
  • Golgi-Cox silver impregnation
  • Prussian Blue (micro bleedings)
Other services:

Microscopy & Imaging
Quantitative Image Analysis
We use sophisticated software solutions
Identification and Detection of Labeled Structures
Analysis of Region and Object Features

Zebrafish Larvae